SQUARIC ACID

PRODUCT IDENTIFICATION
CAS NO. 2892-51-5

SQUARIC ACID

EINECS NO.

220-761-4

FORMULA (HO)2C4(=O)2
MOL WT. 114.06
H.S. CODE 2914.40.9000
TOXICITY  
SYNONYMS Squaric Acid; 3,4-Dihydroxy-3-cyclobutene-1,2-dione; Quadratic acid;
Dihydroxy cyclobutenedione; Quadratic acid; 1,2-Dihydroxycyclobutene-3,4-dione; 1,2-Diketo-3,4-dihydroxycyclobutene; 1,2-Dihydroxy-3,4-cyclobutenedione; 3,4-Dihydroxy-3-cyclobuten-1,2-dion; Quadratsaeure;
SMILES 
C1(C(C(O)=C1O)=O)=O

CLASSIFICATION

Enol

EXTRA NOTES

 A carbon oxoacid that consists of 1,2-diketocyclobut-3-ene bearing two enolic hydroxy substituents at positions 3 and 4. (ChEBI)
Other RN: 94592-78-6

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE white crystalline powder
MELTING POINT 293 C
BOILING POINT  
SPECIFIC GRAVITY  
SOLUBILITY IN WATER 20 (g/l)
AUTOIGNITION 400 C
pH  
VAPOR DENSITY  
NFPA RATINGS  

REFRACTIVE INDEX

  
FLASH POINT

190 C

STABILITY Stable under ordinary conditions.

EXTERNAL LINKS & GENERAL DESCRIPTION

USA.gov - Squaric Acid

Wikipedia Linking - Squaric Acid

Google Scholar Search - Squaric Acid

U.S. National Library of Medicine - Squaric Acid

PubChem Compound Summary - Squaric Acid

http://www.ebi.ac.uk/chebi/ -  Squaric Acid

http://www.ncbi.nlm.nih.gov/ -  Squaric Acid

EPA - Substance Registry Services - Squaric Acid

Local:
Derivatives of squaric acid have a resonance structure which presents an electrostatic mimic for the phosphate group. Squaric acid and its derivatives are used as a replacement for phosphate diester linkages in an oligodeoxynucleotide and phosphates in peptide-based ligands. Squaric acids are used to synthesize inhibitors of protein tyrosine phosphatases in medicinal chemistry. It is used in the synthesis of photosensitive squaraine dyes.

SALES SPECIFICATION

APPEARANCE

 white crystalline powder
ASSAY

99.0% min

WATER

0.1% max

ASH

 0.1% max
TRANSPORTATION
PACKING  
HAZARD CLASS 8 (Packing Group: III)
UN NO.

3261

SAFETY INFORMATION

HAZARD OVERVIEW

GHS (Globally Harmonised System) Classification: Skin irritation. Eye irritation. Skin sensitization. Specific target organ toxicity - single exposure. Hazard statements: Causes skin irritation. May cause an allergic skin reaction. Causes serious eye irritation. May cause respiratory irritation.>

GHS

 

SIGNAL WORD Warning

PICTOGRAMS

HAZARD STATEMENTS

H315-H317-H319-H335

P STATEMENTS

P261-P280-P305 + P351 + P338

EC DIRECTIVES

 

HAZARD CODES

RISK PHRASES

36/37/38-43

SAFETY PHRASES

26-36